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Endoscopic electronic medical record systems.
The loss of cardiac SIRT3 decreases metabolic flexibility and proteostasis in an age-dependent manner.
Targeting ELTD1, an angiogenesis marker for glioblastoma (GBM), also affects VEGFR2: molecular-targeted MRI assessment.
Toll-like receptor 2 signalling: Significance in megakaryocyte development through wnt signalling cross-talk and cytokine induction.
XRN2 interactome reveals its synthetic lethal relationship with PARP1 inhibition.
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Hart, Matthew
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Hart, Matthew
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Alzheimer Disease
Academic Article
Neuroprotective Sirtuin ratio reversed by ApoE4.
Academic Article
Paradoxical effect of TrkA inhibition in Alzheimer's disease models.
Academic Article
Over-expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease.
Academic Article
Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's disease.
Academic Article
Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease.
Academic Article
Vascular mTOR-dependent mechanisms linking the control of aging to Alzheimer's disease.
Academic Article
Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy.
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Alzheimer Disease